Bioinformatics and Systems Biology
Heinrich-Buff-Ring 58,
35392 Giessen
+49-641 99 35801
alexander.goesmann@computation.bio.uni-giessen.de
Research activities of the Goesmann group are focused on the development of innovative bioinformatics software tools in the field of microbial genomics and transcriptomics. Design and implementation of novel features are driven by the close collaboration with partners from various fields of research. As many projects generate experimental data that are produced by high-throughput methods, one of our major tasks is to simplify and automate the subsequent steps of data processing and analysis. Technical work of the group is based on the hardware infrastructure of the Bioinformatics Core Facility (BCF) that provides the necessary storage and compute capacities including a large-scale cloud computing platform with more than 7,500 CPU cores.
genomics and transcriptomics
genome assembly and annotation
metagenomics
comparative genomics
automated data analysis workflows
cloud computing
data management
software engineering
1. Schwengers O, Hoek A, Fritzenwanker M, Falgenhauer L, Hain T, Chakroborty T, Goesmann A (2020) ASA3P: an automatic and scalable pipeline for the assembly, annotation and higher-level analysis of closely related bacterial isolates. doi: 10.1371/journal.pcbi.1007134
2. Blom J, Glaeser SP, Juhre T, Kreis J, Hanel PHG, Schrader JG, Kämpfer P, Goesmann A (2019) EDGAR: A Versatile Tool for Phylogenomics. Bergey's Manual of Systematics of Archaea and Bacteria. doi.org/10.1002/9781118960608.bm00038
3. Jaenicke S, Albaum SP, Blumenkamp P, Linke B, Stoye J, Goesmann A (2018) Flexible metagenome analysis using the MGX framework. Microbiome 24;6(1):76. doi: 10.1186/s40168-018-0460-1
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